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FGF-4人细胞生长因子Recombinant Human FGF-4

  • 更新时间:  2016-04-19
  • 产品型号:  100-31
  • 简单描述
  • Recombinant Human FGF-4 Synonyms:
    Fibroblast Growth Factor-4, HST-1, transforming protein KS3, HBGF-4
详细介绍

 Description:

FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues.
AA Sequence:
GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
Source:
E.coli
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Biological Activity:
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106units/mg.
 
 
 
 
Cross Reactivity:
Mouse, Rat, Human, N/A, Pig
Research Interests:
Angiogenesis/ Cardiovascular Angiogenesis/ Cardiovascular FGF Superfamily FGF Superfamily
Proliferation Proliferation Stem Cells & Differentiation Stem Cells & Differentiation
 
 
Country of Origin:
USA
Research Use Only. Not for use in diagnostic or therapeutic procedures.

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