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RD TOCRIS一级代理,Z-Guggulsterone供应CAS号39025-23-5

  • 更新时间:  2016-04-06
  • 产品型号:  3570
  • 简单描述
  • RD TOCRIS一级代理,Z-Guggulsterone供应CAS号39025-23-5
    我公司代理RD产品和tocris产品
    Z-Guggulsterone
    货号:3570
    规格:10mg,50mg
详细介绍

RD TOCRIS一级代理,Z-Guggulsterone供应CAS号39025-23-5

Catalog Number: 3570

Chemical Name: (Z)-Pregna-4,17(20)-diene-3,16-dione

详细产品信息:

Biological Activity
Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. More active isomer of guggulsterone (Cat. No. 2013).

Technical Data

  • M.Wt:

    312.45

  • Formula:

    C21H28O2

  • Solubility:

    Soluble to 20 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming

  • Purity:

    >98%

  • Storage:

    Store at RT

  • CAS No:

    39025-23-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.


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